Hepatocarcinoma fibrolamelar un tumor de adultos jóvenes poco frecuente. . Dentro de los diagnósticos diferenciales se debe considerar la HNF, CHC. Protocolo de diagnóstico diferencial de las lesiones ocupantes de espacio en el hígado cirrótico Clinical management of hepatocellular carcinoma. Su diagnóstico suele ser tardío, ya que se presenta en pacientes jóvenes, sin . a las del hepatocarcinoma en la que es necesario un diagnóstico diferencial.

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As the gadoxetic acid dose corresponds to one quarter of the habitual extracellular gadolinium dose, the arterial phase acquisition time is critical, requiring temporal precision methods, such as real time visualization of the contrast progression through the arterial system, for the success in this phase acquisition.

FNH presents greater density of functioning hepatocytes than a healthy liver parenchyma, in association with abnormal bile ducts which do not communicate with greater bile ducts, with consequential slower biliary excretion as compared with the surrounding liver. Such contrast agents are absorbed by hepatocytes via OATP1 transporter polypeptide adenosintriphosphate-dependent organic anion transporterthe same as the bilirubin transporter.

Gastrointestinal tumors of childhood. This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. The hepatobiliary contrast may contribute to the diagnosis of cholecystitis as the gallbladder is not filled by the contrast medium, differently from its habitual behavior with other contrast agents.

Magnetic resonance imaging is considered the best imaging method for evaluating such lesions, but does not allow for the diagnosis in all cases. Please review our privacy policy. Contrast uptake is also observed in focal liver lesions with functioning hepatocytes 1.


Fibrolamellar hepatocellular carcinoma: a case report

On the other hand, the enhancement in the hepatobiliary phase is prolonged, allowing for acquisition of images with better spatial resolution, as well as its repetition in case of imaging artifacts 4. Eur J Cancer ; 49 Primary hepatic malignant neoplasms.

The presence of intralesional fat and the absence of hepatobiliary contrast uptake indicate a probable diagnosis of adenoma. Perfusional alterations present a signal similar to the one of the remainder hepatic tissue during the portal and hepatobiliary phases, while most HCCs, except the well-differentiated ones, present hyposignal in the hepatobiliary phase However, the presence of intralesional fat was detected on out-of-phase T1-weighted sequence.

Reporte de un caso.

Prevalence of simple liver cysts and hemangiomas in cirrhotic and non-cirrhotic patients submitted to magnetic resonance imaging. A fraction of hepatobiliary contrast agent is excreted by cMOAT into the biliary canaliculi multispecific canalicular organic anion transporter 1. Considering that the presence of intralesional fat in NFH is rare, the patient will be maintained under imaging follow-up.

Male, year-old patient presenting with chronic C virus hepatopathy. Hepatobiliary contrast uptake by HCCs depends on the tumor differentiation stage and on the amount of functioning hepatocytes 24.

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Journal List Radiol Bras v. Additionally, hepatobiliary contrast agents allow for evaluating the biliary tract 1 – 3. However, in cases of advanced cirrhosis, the contrast uptake by the liver parenchyma may be compromised by decreased hepatocytes function, which would result in reduction of the method’s accuracy to detect HCCs 4 Differential diagnosis of tumors and tumor-like lesions of liver in infancy and childhood.


All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License. In the hepatobiliary phase, the healthy liver is evenly enhanced, becoming hyperintense; the contrast agent hepatocarcinona by the biliary tract occurs progressively, and the blood vessels become hyperintense as compared with the liver parenchyma as the contrast medium is no longer in the vascular compartment.

Adenomas are composed of hepatocytes containing glycogen and lipids surrounded by a capsule. Female, year-old patient undergoing follow-up for metastatic gastrointestinal stromal tumor, with liver nodules to be clarified. As a result, the healthy hepatic tissue remains hyperintense and the metastasis, hypointense, which facilitates its detection 12.

Diagnostic challenges and pitfalls in MR imaging with hepatocyte-specific contrast agents. Two liver nodules are seen in the segment VIII arrows as well as a larger nodule, in the segment VI arrowheadsall of them contrast-enhanced in the arterial-phase, washout in the delayed-phase, and without uptake in the hepatobiliary-phase, characterizing HCCs.

Main indications for hepatobiliary contrast include differentiation between focal nodular hyperplasia FNH and adenoma, characterization of hepatocelular carcinomas HCCsdetection of small liver metastasis, assessment of biliary anatomy, and characterization of postoperative biliary fistulas.

Belo Horizonte, MG, The diagnosis of sphincter of Oddi dysfunction can be based on the finding of absent or delayed passage of the hepatobiliary contrast thru the ampulla of Vater.

GCR ; 6 1: